Over the past few years I have worked a bit on PC imaging, more along the Windows environment. In that time there were a lot of sites that I have visited that deal with tips on how to make your computer a little more pleasurable.
The folks over at WWW.Annoyances.Org have a very extensive list of helpful tips and tricks. They also have a search feature that can help you find the changes you want.
PLEASE be aware, if you find something and want make changes to the registry or start deleting files on your computer you might cause more harm than good. Make sure you follow the directions to the letter or you can stop your computer from working. Yes I have caused major problems in our computer lab, to the point that it would not even boot up.